| 1 | Space Jam: A New Legacy | Warner Bros. | 1 | PG | 3,965 | - | $31,053,362 | - | $7,832 | $31,053,362 |
| 2 | Black Widow | Walt Disney Studios | 2 | PG-13 | 4,275 | 115 | $25,847,496 | -67.8% | $6,046 | $131,609,167 |
| 3 | Escape Room: Tournament of Champions | Sony Pictures Entertainment (SPE) | 1 | PG-13 | 2,815 | - | $8,800,000 | - | $3,126 | $8,800,000 |
| 4 | F9: The Fast Saga | Universal Pictures | 4 | PG-13 | 3,368 | -281 | $7,673,715 | -32.9% | $2,278 | $154,892,670 |
| 5 | The Boss Baby: Family Business | Universal Pictures | 3 | PG | 3,449 | -239 | $4,730,085 | -46.7% | $1,371 | $44,651,760 |
| 6 | The Forever Purge | Universal Pictures | 3 | R | 2,735 | -323 | $4,115,830 | -42.4% | $1,505 | $35,866,540 |
| 7 | A Quiet Place Part II | Paramount Pictures | 8 | PG-13 | 1,995 | -364 | $2,238,015 | -29.1% | $1,122 | $154,965,885 |
| 8 | Roadrunner: A Film About Anthony Bourdain | Focus Features | 1 | R | 927 | - | $1,988,795 | - | $2,145 | $1,988,795 |
| 9 | Cruella | Walt Disney Studios | 8 | PG-13 | 1,175 | -700 | $1,165,810 | -50.8% | $992 | $83,483,327 |
| 10 | Pig | Neon | 1 | R | 552 | - | $970,935 | - | $1,759 | $970,935 |
| 11 | The Hitman’s Wife’s Bodyguard | Lionsgate | 6 | R | 1,034 | -870 | $766,474 | -53% | $741 | $36,664,605 |
| 12 | Peter Rabbit 2: The Runaway | Sony Pictures Entertainment (SPE) | 6 | PG | 1,117 | -841 | $605,000 | -52.1% | $542 | $39,297,319 |
| 13 | In the Heights | Warner Bros. | 6 | PG-13 | 418 | -987 | $372,297 | -39.2% | $891 | $29,090,815 |
| 14 | The Conjuring: Devil Made Me Do It | Warner Bros. | 7 | R | 390 | -1,326 | $353,137 | -46.1% | $905 | $64,577,677 |
| 15 | Le Guide de la Famille Parfaite | Independent | 1 | TV-14 | 76 | - | $268,665 | - | $3,535 | $268,665 |
| 16 | Summer of Soul (…Or, When the Revolution Could Not Be Televised) | Searchlight Pictures | 3 | PG-13 | 275 | -477 | $180,985 | -52.1% | $658 | $1,872,351 |
| 17 | 12 Mighty Orphans | Sony Pictures Entertainment (SPE) | 6 | PG-13 | 140 | -45 | $88,166 | -35.4% | $630 | $3,326,335 |
| 18 | Spirit Untamed | Universal Pictures | 7 | PG | 910 | -58 | $58,115 | -58.5% | $64 | $17,487,395 |
| 19 | I Carry You With Me | Sony Pictures Classics | 4 | R | 111 | 54 | $26,356 | -14.6% | $237 | $135,156 |
| 20 | Raya and the Last Dragon | Walt Disney Studios | 20 | PG | 41 | -14 | $15,291 | -54.5% | $373 | $54,620,871 |
| 21 | Werewolves Within | IFC Films | 4 | R | 46 | -17 | $15,064 | -39.8% | $327 | $557,413 |
| 22 | Witnesses | Purdie Distribution | 7 | PG | 21 | -7 | $13,476 | -33% | $642 | $771,375 |
| 23 | Mama Weed | Music Box Films | 1 | NR | 20 | - | $8,891 | - | $445 | $8,891 |
| 24 | The Truffle Hunters | Sony Pictures Classics | 15 | PG-13 | 15 | -3 | $8,425 | -26.7% | $562 | $464,264 |
| 25 | Wrath of Man | United Artists Releasing | 11 | R | 45 | -5 | $8,112 | -34.8% | $180 | $27,454,233 |
| 26 | Rita Moreno: Just a Girl Who Decided to Go for It | Roadside Attractions | 5 | PG-13 | 16 | -7 | $4,544 | -22.6% | $284 | $257,986 |
| 27 | Summer of 85 | Music Box Films | 5 | NR | 10 | -3 | $3,628 | -29% | $363 | $67,120 |
| 28 | Can You Bring It: Bill T. Jones and D-Man in the Waters | Kino Lorber | 1 | NR | 1 | - | $2,558 | - | $2,558 | $2,558 |
| 29 | The Dry | IFC Films | 9 | R | 5 | -2 | $2,012 | -44.5% | $402 | $360,339 |
| 30 | Undine | IFC Films | 7 | NR | 4 | -3 | $1,680 | -19.3% | $420 | $77,560 |
| 31 | A Soldier’s Story 2: Return from the Dead | Indican Pictures | 4 | NR | 2 | 0 | $436 | -74.7% | $218 | $19,452 |
| 32 | Truman & Tennessee: An Intimate Conversation | Kino Lorber | 5 | - | 3 | -10 | $280 | 0% | $93 | $53,312 |
| 33 | The Perfect Candidate | Music Box Films | 9 | NR | 1 | 0 | $47 | -58.8% | $47 | $28,664 |
